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We Can No Longer Ignore the Potential of Psychedelic Drugs to Treat Depression

By Robin Carhart-Harris — 2020

At Imperial College we’ve been comparing psilocybin to conventional antidepressants—and the results are likely to be game-changing.

Read on www.theguardian.com

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The Psychedelic Revolution Is Coming. Psychiatry May Never Be the Same.

Though researchers are still trying to understand the cognitive and therapeutic mechanics of psychedelics, they have concluded that psilocybin, DMT and other psychoactive chemicals can help people feel more tolerance, understanding and empathy.

Article
Andrew Jacobs
2021
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Introducing Ayahuasca

Amazonian healing traditions collide with Western medical sensibilities.

Article
Zoe Jahn, Monnica T. Williams
2019
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Mind Molding Psychedelic Drugs Could Treat Depression, and Other Mental Illnesses

It seems that psychedelics do more than simply alter perception. According to the latest research from my colleagues and me, they change the structures of neurons themselves.

Article
David E. Olson
2018
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Largest Ever DMT Survey Travels to the Fringes of Psychedelic Science

Encounters with inter-dimensional beings, atheists discovering belief, and the bizarre world of DMT-induced entities. A trip to the fringes of psychedelic science.

Article
Rich Haridy
2020
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Ayahuasca Produces Long-Lasting Changes in the Brain

The powerful hallucinogenic brew provokes long-lasting changes in two important brain networks.

Article
Tibi Puiu
2020
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Ayahuasca Could Do Something Amazing to Your Brain, Study Shows

Science is finally catching up with the potential powers of this psychedelic drink.

Article
Caroline Delbert
2020
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A Model for the Application of Target-Controlled Intravenous Infusion for a Prolonged Immersive DMT Psychedelic Experience

Using pharmacokinetic modeling and DMT blood sampling data, we demonstrate that the unique pharmacological characteristics of DMT, which also include a rapid onset and lack of acute tolerance to its subjective effects, make it amenable to administration by target-controlled intravenous infusion.

Article
Andrew R. Gallimore and Rick J. Strassman
2016
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Chronic, Intermittent Microdoses of the Psychedelic N,N-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents

Taken together, our results suggest that psychedelic microdosing may alleviate symptoms of mood and anxiety disorders, though the potential hazards of this practice warrant further investigation.

Article
Lindsay P. Cameron, Charlie J. Benson, Brian C. DeFelice, Oliver Fiehn, and David E. Olson
2019
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DMT Alters Cortical Travelling Waves

These results support a recent model proposing that psychedelics reduce the ‘precision-weighting of priors’, thus altering the balance of top-down versus bottom-up information passing.

Article
Andrea Alamia, Christopher Timmermann, David J Nutt, Rufin VanRullen, Robin L Carhart-Harris
2020
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DMT Models the Near-Death Experience

Near-death experiences (NDEs) are complex subjective experiences, which have been previously associated with the psychedelic experience and more specifically with the experience induced by the potent serotonergic, N,N-Dimethyltryptamine (DMT).

Article
Christopher Timmermann, Leor Roseman, Luke Williams, David Erritzoe, Charlotte Martial, Héléna Cassol, Steven Laureys, David Nutt and Robin Carhart-Harris
2018
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Psilocybin