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Core Symptoms of Major Depressive Disorder: Relevance to Diagnosis and Treatment

By Sidney H. Kennedy — 2008

The construct of major depressive disorder makes no etiological assumptions about populations with diverse symptom clusters. “Depressed mood” and “loss of interest or pleasure in nearly all activities” are core features of a major depressive episode, though a strong case can be made to pay increasing attention to symptoms of fatigue, sleep disturbance, anxiety, and neurocognitive and sexual dysfunction in the diagnosis and evaluation of treatment outcome.

Read on www.ncbi.nlm.nih.gov

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Ketamine Therapy Is Going Mainstream. Are We Ready?

The mind-altering drug has been shown to help people suffering from anxiety and depression. But how it helps, who it will serve, and who will profit are open questions.

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Ketamine Is Revealing a New Understanding of Depression and the Brain

Some experts view ketamine as a tool to unravel the biological causes of depression and, perhaps someday, cure it.

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Can Ketamine Treat Depression? the Answer May Lie in a Mysterious Brain Cell

To treat depression, the neurons which control the hormones serotonin and dopamine in our brains seem to get all the attention.

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One Dose of ‘Magic Mushroom’ Drug Reduces Anxiety and Depression in Cancer Patients, Study Says

A single dose of psilocybin, a compound found in “magic mushrooms,” provides long-term relief of anxiety and depression in cancer patients, a new study finds.

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Single Dose of Psychedelic Drug Eased Cancer Patients’ Anxiety, Depression for Years

The new research looked at cancer patients who took part in a study nearly five years ago.

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Are Psychedelics the Answer to Depression and Addiction?

A new generation of research into psilocybin could change how we treat numerous mental health conditions.

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Clinical Depression