MDMA, commonly known as ecstasy or molly, is a synthetic psychoactive drug that is commonly associated with recreational use at raves or clubs, but it has more recently been studied along with other psychedelics in the treatment of a variety of ailments, most specifically post-traumatic stress disorder (PTSD). Other uses under study have been to treat depression, social anxiety, and (in couples therapy) to foster closeness. Common effects of the drug include euphoria, heightened empathy, and a sense of emotional well-being, along with a more intense experience of colors and sounds. While MDMA has been moved under review of the Food and Drug Administration in the US for clinical use, it still remains illegal in most countries.

Can MDMA Be Used to Treat PTSD?

Although ecstasy has been linked to long-term neurological effects and even death—associations that some experts dispute—MDMA has proven safe and non-addictive in some clinical studies. Moreover, MDMA may be effective when combined with psychotherapy to treat PTSD.

MDMA’s Journey from Molly to Medicine

MDMA-assisted psychotherapy readies for phase III trials, a last step before possible prescription use in PTSD patients.

A Psychedelic Drug Passes Big Test for PTSD Treatment

In an important step toward medical approval, MDMA, the illegal drug popularly known as Ecstasy or Molly, was shown to bring relief to those suffering from severe post-traumatic stress disorder when paired with talk therapy.

MDMA Steps Closer to FDA Approval as a Drug, But Now It Needs to Leap

The Multidisciplinary Association for Psychedelic Studies believes that MDMA-assisted psychotherapy could be legal by 2021.

MDMA-Assisted Couples Therapy: How a Psychedelic Is Enhancing Intimacy and Healing PTSD

Research over the last decade has shown MDMA-assisted psychotherapy to be effective in treating PTSD from military combat, sexual assault and childhood abuse. Now researchers are trialing MDMA with couples and finding promising results.

Who Will Benefit From Psychedelic Medicine?

These substances are being touted as a game-changing intervention for mental health. But it’s not clear if their promise will be accessible to all.

The Interview: MDMA-Therapy Expert Dr. Rick Doblin

The world’s leading advocate for the medicinal use of psychedelics on the ghost of Timothy Leary, why Ecstasy could cure PTSD, and the best place to trip in Boston.

MDMA, or Ecstasy, Shows Promise as a PTSD Treatment

Scientists test how pharmaceutical-grade MDMA combines with psychotherapy to help patients with a severe form of PTSD.

MDMA Lauded as ‘Breakthrough’ Therapy for PTSD Patients

The Food and Drug Administration (FDA) has approved the design of two Phase 3 clinical trials of MDMA for treating PTSD, according to the Multidisciplinary Association for Psychedelic Studies (MAPS), which is funding and leading the clinical trials.

Ecstasy as a Remedy for PTSD? You Probably Have Some Questions.

The drug known by the street names Ecstasy or Molly could be a promising treatment for post-traumatic stress disorder, according to a new study.


Psychedelic-Assisted Therapy