By Ed Prideaux — 2021
The growing legitimacy of psychedelics as therapies promises to transform how we view the extraordinary, writes Ed Prideaux.
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CLEAR ALL
Encounters with inter-dimensional beings, atheists discovering belief, and the bizarre world of DMT-induced entities. A trip to the fringes of psychedelic science.
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The powerful hallucinogenic brew provokes long-lasting changes in two important brain networks.
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Science is finally catching up with the potential powers of this psychedelic drink.
The antidepressant effects of the psychedelic brew known as ayahuasca appear to be related to anti-inflammatory activity, according to new research from scientists in Brazil.
Using pharmacokinetic modeling and DMT blood sampling data, we demonstrate that the unique pharmacological characteristics of DMT, which also include a rapid onset and lack of acute tolerance to its subjective effects, make it amenable to administration by target-controlled intravenous infusion.
Taken together, our results suggest that psychedelic microdosing may alleviate symptoms of mood and anxiety disorders, though the potential hazards of this practice warrant further investigation.
These results support a recent model proposing that psychedelics reduce the ‘precision-weighting of priors’, thus altering the balance of top-down versus bottom-up information passing.
Research into psychedelics, shut down for decades, is now yielding exciting results.
Last month, Ian McCall told HBO’s Real Sports that his 17 years in mixed martial arts led him to a painkiller addiction. “I was medicated and so numbed out from such a young age, I turned into a monster,” he told correspondent David Scott.
Williams is the co-lead author of a recent retrospective study that found those who tried doses of psilocybin (more commonly known as magic mushrooms), LSD, or MDMA (the pure substance found in Ecstasy or Molly) reported a decrease in trauma symptoms, depression and anxiety after 30 days.