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The Movement to Decriminalize Psilocybin, Explained

By Dustin Marlan — 2021

The latest frontier in state and local drug reform has been the loosening of legal restrictions on psilocybin—the psychoactive compound in “magic mushrooms.”

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Rapid Antidepressant Effects of the Psychedelic Ayahuasca Linked to Changes in Inflammatory Biomarkers

The antidepressant effects of the psychedelic brew known as ayahuasca appear to be related to anti-inflammatory activity, according to new research from scientists in Brazil.

Article
Eric W. Dolan
2021
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A Model for the Application of Target-Controlled Intravenous Infusion for a Prolonged Immersive DMT Psychedelic Experience

Using pharmacokinetic modeling and DMT blood sampling data, we demonstrate that the unique pharmacological characteristics of DMT, which also include a rapid onset and lack of acute tolerance to its subjective effects, make it amenable to administration by target-controlled intravenous infusion.

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Andrew R. Gallimore and Rick J. Strassman
2016
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Chronic, Intermittent Microdoses of the Psychedelic N,N-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents

Taken together, our results suggest that psychedelic microdosing may alleviate symptoms of mood and anxiety disorders, though the potential hazards of this practice warrant further investigation.

Article
Lindsay P. Cameron, Charlie J. Benson, Brian C. DeFelice, Oliver Fiehn, and David E. Olson
2019
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DMT Alters Cortical Travelling Waves

These results support a recent model proposing that psychedelics reduce the ‘precision-weighting of priors’, thus altering the balance of top-down versus bottom-up information passing.

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Andrea Alamia, Christopher Timmermann, David J Nutt, Rufin VanRullen, Robin L Carhart-Harris
2020
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Mixing Magic Mushrooms and Meditation Has Long-Term Benefits, Johns Hopkins Study Finds

The benefits of controlled psilocybin use and spiritual practice on people's well-being long outlast the high, researchers find.

Article
Teodora Zareva
2018
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The Trip Treatment

Research into psychedelics, shut down for decades, is now yielding exciting results.

Article
Michael Pollan
2015
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UFC Eyes Psychedelics as Therapy for Fighters’ Brain Injuries

Last month, Ian McCall told HBO’s Real Sports that his 17 years in mixed martial arts led him to a painkiller addiction. “I was medicated and so numbed out from such a young age, I turned into a monster,” he told correspondent David Scott.

Article
Dustin Foote
2021
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Psychedelic Drugs Can Help Treat PTSD Caused by Racism, Discrimination: Researchers

Williams is the co-lead author of a recent retrospective study that found those who tried doses of psilocybin (more commonly known as magic mushrooms), LSD, or MDMA (the pure substance found in Ecstasy or Molly) reported a decrease in trauma symptoms, depression and anxiety after 30 days.

Article
Avis Favaro, Elizabeth St. Philip, Solarina Ho
2021
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How Ecstasy and Psilocybin Are Shaking Up Psychiatry

Regulators will soon grapple with how to safely administer powerful psychedelics for treating depression and post-traumatic stress disorder.

Article
Paul Tullis
2021
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MDMA Lauded as ‘Breakthrough’ Therapy for PTSD Patients

The Food and Drug Administration (FDA) has approved the design of two Phase 3 clinical trials of MDMA for treating PTSD, according to the Multidisciplinary Association for Psychedelic Studies (MAPS), which is funding and leading the clinical trials.

Article
Maureen Meehan
2017
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